Hu, Guang-Qi; Bai, Jing-Wen; Li, En-Ci; Liu, Kai-Hui; Sheng, Fei-Fei; Zhang, Hong-Hai published an article in 2021. The article was titled 《Synthesis of Multideuterated (Hetero)aryl Bromides by Ag(I)-Catalyzed H/D Exchange》, and you may find the article in Organic Letters.Reference of 1-Bromo-2-isopropylbenzene The information in the text is summarized as follows:
Herein, a direct H/D exchange protocol was disclosed for deuteration of (hetero)aryl bromides using Ag2CO3 as catalyst and D2O as deuterium source. This protocol was highly efficient, simply manipulated and appliable for deuterium-labeling of over 55 (hetero)aryl bromides including bioactive druglike mols. and key intermediates of functional materials. In addition, this method showed distinguishing site-selectivity toward the existing transition-metal-catalyzed HIE process, leading to multideuterated (hetero)aryl bromides in one step. In the experiment, the researchers used many compounds, for example, 1-Bromo-2-isopropylbenzene(cas: 7073-94-1Reference of 1-Bromo-2-isopropylbenzene)
1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. The most pervasive is the naturally produced bromomethane.Reference of 1-Bromo-2-isopropylbenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary