《Synthesis of Vinylic Sulfones in Aqueous Media》 was written by Goh, Jeffrey; Maraswami, Manikantha; Loh, Teck-Peng. Application In Synthesis of Benzyl 2-bromoacetateThis research focused onvinylic sulfone green preparation regioselective; allenic carbonyl compound sulfinic acid sulfination. The article conveys some information:
A green method for the sulfination of allenic carbonyl compounds to access a wide variety of vinylic sulfones RC(O)CH2C(SO2R1)=CH2 [R = hexyl, Ph, 2-furyl, etc.; R1 = Me, cyclopropyl, Ph, etc.] was developed. This reaction worked in aqueous media under very mild conditions. This reaction was atom economic. A wide variety of vinylic sulfones could be obtained in moderate to excellent yields with wide functional group tolerance. The efficiency of this method was demonstrated in some reactions where the desired products could be isolated by filtration. After reading the article, we found that the author used Benzyl 2-bromoacetate(cas: 5437-45-6Application In Synthesis of Benzyl 2-bromoacetate)
Benzyl 2-bromoacetate(cas: 5437-45-6) has been used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.Application In Synthesis of Benzyl 2-bromoacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary