《Synthesis and evaluation of aromatic methoxime derivatives against five postharvest phytopathogenic fungi of fruits. Main structure-activity relationships》 was written by Cortes, Ivan; di Liberto, Melina G.; Kaufman, Teodoro S.; Derita, Marcos G.; Bracca, Andrea B. J.. Safety of 8-Bromooctanoic acid And the article was included in Food Chemistry in 2020. The article conveys some information:
The antifungal activity of a library of twenty-four aromatic methoximes was examined against five representative postharvest phytopathogenic fungi. The panel included Penicillium digitatum, Penicillium italicum, Rhizopus stolonifer, Botrytis cinerea and Monilinia fructicola, all of which cause relevant economic losses worldwide as a result of affecting harvested fruits. The min. inhibitory concentrations and min. fungicidal concentrations of each compound were defined and the main structure-activity relationships were determined Although other congeners were more potent, drug likeliness considerations pointed to the methoxime derived from 2,4-dihydroxypropiophenone as the compound with the most suitable profile. The morphol. of the colonies of the fungal strains treated with the methoxime was examined microscopically and the compound was also tested in freshly harvested peaches and oranges, exhibiting promising control profiles in both fruits, similar to those of the com. agents Imazalil and Carbendazim. The experimental part of the paper was very detailed, including the reaction process of 8-Bromooctanoic acid(cas: 17696-11-6Safety of 8-Bromooctanoic acid)
8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid. And 8-Bromooctanoic Acid is a useful compound for sonodynamic therapy.Safety of 8-Bromooctanoic acid
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary