Category: bromides-buliding-blocksIn 2022 ,《Iron-Catalyzed Ring Expansion of Cyclobutanols for the Synthesis of 1-Pyrrolines by Using MsONH3OTf》 appeared in Organic Letters. The author of the article were Zhuang, Daijiao; Gatera, Tharcisse; An, Zhenyu; Yan, Rulong. The article conveys some information:
The synthesis of 1-pyrrolines I [R = Ph, 4-MeC6H4, 2-thienyl, etc.; R1 = H, Bn, 4-MeOC6H4CH2] from cyclobutanol derivatives and aminating reagent (MsONH3OTf) had been developed. This one-pot procedure achieved C-N single bond/C = N double bond formation via ring expansion reaction. A series of 1-pyrroline derivatives was synthesized in moderate to good yields under mild conditions. In addition to this study using 5-Bromobenzo[d][1,3]dioxole, there are many other studies that have used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Category: bromides-buliding-blocks) was used in this study.
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary