In 2019,Organic Letters included an article by Tian, Ming-Qing; Wang, Cong; Hu, Xu-Hong; Loh, Teck-Peng. Synthetic Route of C4H7Br. The article was titled 《Divergent C-H Oxidative Radical Functionalization of Olefins to Install Tertiary Alkyl Motifs Enabled by Copper Catalysis》. The information in the text is summarized as follows:
An efficient tertiary alkylation reaction of olefins with 1,3-dicarbonyl compounds was developed by virtue of copper catalyst without the use of expensive ligands or additives. In contrast to alkyl Heck-type reaction, alkyl halide is not required. Notably, by varying the nitrogen and air atm., the reaction selectively produces alkylation and alkylation-oxygenation products, resp. Initial investigations revealed that an α-carbonyl alkyl radical species might be involved in the process. In addition to this study using (Bromomethyl)cyclopropane, there are many other studies that have used (Bromomethyl)cyclopropane(cas: 7051-34-5Synthetic Route of C4H7Br) was used in this study.
(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Synthetic Route of C4H7Br
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary