《Nickel-catalyzed reductive coupling of homoenolates and their higher homologues with unactivated alkyl bromides》 was written by Lin, Tingzhi; Gu, Yuanyun; Qian, Pengcheng; Guan, Haixing; Walsh, Patrick J.; Mao, Jianyou. HPLC of Formula: 7051-34-5 And the article was included in Nature Communications in 2020. The article conveys some information:
A nickel-catalyzed generation of homoenolates, and their higher homologues, via decarbonylation of readily available cyclic anhydrides was developed. The utility of nickel-bound homoenolates and their higher homologues was demonstrated by cross-coupling with unactivated alkyl bromides, generated a diverse array of aliphatic acids. A broad range of functional groups was tolerated. Preliminary mechanistic studies demonstrated that the oxidative addition of anhydrides by the catalyst was faster than oxidative addition of alkyl bromides. The nickel bound metallocycles were involved in this transformation. The catalyst undergoes a single electron transfer (SET) process with the alkyl bromide. In the experiment, the researchers used (Bromomethyl)cyclopropane(cas: 7051-34-5HPLC of Formula: 7051-34-5)
(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.HPLC of Formula: 7051-34-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary