《Direct C(sp2)-H alkylation of unactivated arenes enabled by photoinduced Pd catalysis》 was published in Nature Communications in 2020. These research results belong to Kim, Daeun; Lee, Geun Seok; Kim, Dongwook; Hong, Soon Hyeok. Quality Control of (Bromomethyl)cyclopropane The article mentions the following:
Here, the catalytic C(sp2)-H alkylation reactions of unactivated arenes with alkyl bromides via visible-light induced Pd catalysis was reported. The reaction proceeded smoothly under mild conditions without any skeletal rearrangement of the alkyl groups. The direct syntheses of structurally diverse linear and branched alkylarenes, including the late-stage phenylation of biol. active mols. and an orthogonal one-pot sequential Pd-catalyzed C-C bond-forming reaction, were achieved with exclusive chemoselectivity and exceptional functional group tolerance. Comprehensive mechanistic investigations through a combination of exptl. and computational methods revealed a distinguishable Pd(0)/Pd(I) redox catalytic cycle and the origin of the counter-intuitive reactivity differences among alkyl halides. In addition to this study using (Bromomethyl)cyclopropane, there are many other studies that have used (Bromomethyl)cyclopropane(cas: 7051-34-5Quality Control of (Bromomethyl)cyclopropane) was used in this study.
(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Quality Control of (Bromomethyl)cyclopropane
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary