The author of 《Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes》 were Iosub, Andrei V.; Moravcik, Stefan; Wallentin, Carl-Johan; Bergman, Joakim. And the article was published in Organic Letters in 2019. Product Details of 17696-11-6 The author mentioned the following in the article:
The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, di-Me dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overredn. to alcs. Moreover, this methodol. is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot use of the aldehyde products.8-Bromooctanoic acid(cas: 17696-11-6Product Details of 17696-11-6) was used in this study.
8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid. And 8-Bromooctanoic Acid is a useful compound for sonodynamic therapy.Product Details of 17696-11-6
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary