In 2022,Grantham, Helena F.; Kimber, Marc C. published an article in ChemPhotoChem. The title of the article was 《Dimeric Cyclobutane Formation Under Continuous Flow Conditions Using Organophotoredox-Catalyzed [2+2] Cycloaddition》.Product Details of 6825-20-3 The author mentioned the following in the article:
By merging organophotoredox catalysis and continuous flow technol., a batch vs. continuous flow study was performed providing a convenient synthetic route to an important carbazole cyclobutane material dimer 1,2-trans-dicarbazylcyclobutane (t-DCzCB) using only 0.1 mol % of an organophotoredox catalyst. The scope of this methodol. was explored giving a new class of functional materials, as well as an improved synthetic route to styrene-based lignan dimeric natural products. The cyclobutane dimers were isolated in higher chem. yields under continuous flow conditions and reaction times were reduced significantly compared to traditional batch reaction conditions. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Product Details of 6825-20-3)
3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Product Details of 6825-20-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary