In 2016,Gildner, Peter G.; DeAngelis, Andrew; Colacot, Thomas J. published 《Palladium-Catalyzed N-Arylation of Cyclopropylamines》.Organic Letters published the findings.Computed Properties of C9H11Br The information in the text is summarized as follows:
A general method has been developed for the previously challenging arylation of cyclopropylamine and N-arylcyclopropylamines. Highly active, air-stable, and com. available R-allylpalladium precatalysts provide access to a wide range of (hetero)arylated cyclopropylanilines in high yields. Precatalysts [(tBuBrettPhos)Pd(allyl)]OTf and [(BrettPhos)Pd(crotyl)]OTf deliver monoarylated products, while (PtBu3)Pd(crotyl)Cl is suited for preparing unsym. diarylated products. The developed conditions tolerate a range of functional groups and heterocycles, allowing access to an array of arylated cyclopropylamines, a motif present in prominent drug mols.1-Bromo-2-isopropylbenzene(cas: 7073-94-1Computed Properties of C9H11Br) was used in this study.
1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Computed Properties of C9H11Br
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary