Furniel, Lucas G.; Echemendia, Radell; Burtoloso, Antonio C. B. published their research in Chemical Science in 2021. The article was titled 《Cooperative copper-squaramide catalysis for the enantioselective N-H insertion reaction with sulfoxonium ylides》.COA of Formula: C7H5BrO2 The article contains the following contents:
The first examples of a highly efficient and enantioselective carbene-mediated insertion reaction, from a sulfur ylide, were described. By way of a catalytic asym. insertion reaction into N-H bonds from carbonyl sulfoxonium ylides and anilines, using a copper-bifunctional squaramide cooperative catalysis approach, thirty-seven α-arylglycine esters were synthesized in enantiomeric ratios up to 92:8 (99:1 after a single recrystallization) and reaction yields ranging between 49-96%. Furthermore, the protocol benefited from quick reaction times and was conducted in a straightforward manner. The experimental process involved the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4COA of Formula: C7H5BrO2)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.COA of Formula: C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary