Product Details of 586-76-5In 2020 ,《A recyclable, metal-free mechanochemical approach for the oxidation of alcohols to carboxylic acids》 appeared in Molecules. The author of the article were Denlinger, Kendra Leahy; Carr, Preston; Waddell, Daniel C.; Mack, James. The article conveys some information:
The oxidation of primary alcs. under mechanochem. conditions in a Spex8000M Mixer/Mill was investigated. To facilitate ease of separation and recyclability, a polystyrene-bound version of a TEMPO catalyst was employed. When paired with Oxone in a stainless-steel vial with a stainless-steel ball, several primary alcs. were successfully oxidized to the corresponding carboxylic acids. The product was isolated using gravity filtration, which also allowed for the polystyrene-bound TEMPO catalyst to be recovered and reused in subsequent oxidation reactions. Furthermore, it was demonstrated that the size and steric hindrance of the primary alc. does not hinder the rate of the reaction. Finally, the aldehyde was selectively obtained from a primary alc. under ball milling conditions by using a combination of non-supported TEMPO with a copper vial and copper ball. In the part of experimental materials, we found many familiar compounds, such as 4-Bromobenzoic acid(cas: 586-76-5Product Details of 586-76-5)
4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Product Details of 586-76-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary