In 2022,Belitz, Florian; Seitz, Ann-Katrin; Goebel, Jonas F.; Hu, Zhiyong; Goossen, Lukas J. published an article in Organic Letters. The title of the article was 《Ru-Catalyzed C-H Arylation of Acrylic Acids with Aryl Bromides》.Formula: C7H5BrO2 The author mentioned the following in the article:
In the presence of a [Ru(p-cymene)Cl2]2/triethylphosphine/lithium carbonate catalyst system, aryl bromides underwent (Z)-selective couplings with unprotected 2-arylacrylic acids to form (Z)-1,2-diarylacrylic acids. This vinylic C-H functionalization proceeds in high yields of up to 94% and (Z/E)-ratios of up to 99:1, tolerating a wide range of functional groups. Mechanistic studies indicate that the vinylic C-H activation proceeds via base-assisted cyclometalation rather than via a Heck-type mechanism, which explains its orthogonal stereoselectivity.5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Formula: C7H5BrO2) was used in this study.
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Formula: C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary