《Base- and Catalyst-Induced Orthogonal Site Selectivities in Acylation of Amphiphilic Diols》 was published in Organic Letters in 2020. These research results belong to Ashush, Natali; Fallek, Reut; Fallek, Amit; Dobrovetsky, Roman; Portnoy, Moshe. SDS of cas: 17696-11-6 The article mentions the following:
Seeking to selectively functionalize natural and synthetic amphiphiles, we explored acylation of model amphiphilic diols. The use of a nucleophilic catalyst enabled a remarkable shift of the site selectivity from the polar site, preferred in background noncatalyzed or base-promoted reactions, to the apolar site. This tendency was significantly enhanced for organocatalysts comprising an imidazole active site surrounded by long/branched tails. An explanation of these orthogonal modes of selectivity is supported by competitive experiments with monoalc. substrates. The experimental process involved the reaction of 8-Bromooctanoic acid(cas: 17696-11-6SDS of cas: 17696-11-6)
8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid.SDS of cas: 17696-11-6
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary