In 2022,Zhong, Qidi; Wang, Yinxin; Lan, Hanyang; Zhu, Hao; Fan, Qiangwen published an article in Journal of Organic Chemistry. The title of the article was 《Construction of 3,12-Diazatetracyclododecane-dienes through Unexpected Visible-Light-Induced Radical Cascade Cyclization》.Application In Synthesis of (Bromomethyl)cyclopropane The author mentioned the following in the article:
A novel visible-light-induced cascade radical cyclization reaction of 3-cyano-4-aryl-1,4-dihydropyridines I (R1 = cyclopropylmethyl, benzyl, 4-chlorobenzyl, naphthalen-2-ylmethyl, etc.; R2 = Ph, 4-chlorophenyl, 3-methylphenyl, 2-fluorophenyl, etc.) for the construction of 3,12-diazatetracyclododecane-diene derivatives II is reported for the first time. In the presence of 410 nm blue LED lamp as the light source and ethanol as the solvent, the reactions proceed smoothly to afford photocyclization products in good yields. The process is carried out through the breaking of original C=C double bonds and the formation of three new single bonds in one pot and proved to be able to tolerate different substituents. The experimental process involved the reaction of (Bromomethyl)cyclopropane(cas: 7051-34-5Application In Synthesis of (Bromomethyl)cyclopropane)
(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Application In Synthesis of (Bromomethyl)cyclopropane
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary