In 2022,Yao, Chengbo; Williams, Alana D. N.; Gu, Yiting; Norton, Jack R. published an article in Journal of Organic Chemistry. The title of the article was 《Isomerization of Aziridines to Allyl Amines via Titanium and Chromium Cooperative Catalysis》.Safety of Ethyltriphenylphosphonium bromide The author mentioned the following in the article:
A Ti/Cr cooperative catalyst isomerized aziridines to allyl amines under mild conditions. The reaction tolerated a broad range of aziridines with various nitrogen substituents. The titanium catalyst was most successful in opening 1,2-disubstituted aziridines, forming radical intermediates in a highly regioselective manner. The chromium catalyst appears to abstract an H• from these radical intermediates and then return the H• to the titanium system in the form of an H+ and an electron. The reaction was complementary to previous reports on the isomerization of aziridines to allyl amines. After reading the article, we found that the author used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Safety of Ethyltriphenylphosphonium bromide)
Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Safety of Ethyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary