On July 21, 2022, Yang, Dun; Zhang, Jing; Zhang, Shenqiu; Allen, Thaddeus; Shi, Qiong; Nimishetti, Naganna; Huang, Jian; Li, Hongmei; Yang, Chenglu published a patent.Related Products of 259231-26-0 The title of the patent was Preparation of fused azepine compounds and their use in the treatment of cancer. And the patent contained the following:
The invention relates to fused azepines of formula I and pharmaceutically acceptable salts thereof; their preparation and use in the treatment of cancer. Compounds of formula I, wherein X is O and S; ring A is (un)substituted Ph, (un)substituted 6-membered heteroaryl; L is a bond, CO, SO2, etc.; each R1 is independently halo, CN, (un)substituted Ph, etc.; each R2 is H, CN, (un)substituted Ph, etc.; each R3 is (un)substituted Ph, (un)substituted heteroaryl, (un)substituted 3- to 7-membered carbocyclyl, etc.; m = 0 – 4; p = 0 – 5; and pharmaceutically acceptable salts thereof, are claimed. Example compound II was prepared by condensation of Me 5-hydroxy-2-oxo-2,3-dihydro-1H-benzo[b]azepine-4-carboxylate with (bromomethyl)benzene. The invention compounds were evaluated for their anticancer activities (some data given). The experimental process involved the reaction of 2-Bromo-4-(bromomethyl)-1-methylbenzene(cas: 259231-26-0).Related Products of 259231-26-0
The Article related to fused azepine treatment cancer preparation, Heterocyclic Compounds (One Hetero Atom): Higher-Membered Rings and other aspects.Related Products of 259231-26-0
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary