In 2019,Organic & Biomolecular Chemistry included an article by Sun, Wan; Chen, Chen; Qi, Yuan; Zhao, Jinghui; Bao, Yinwei; Zhu, Bolin. Recommanded Product: Methyltriphenylphosphonium bromide. The article was titled 《Palladium-catalyzed cascade reactions of alkene-tethered carbamoyl chlorides with N-tosyl hydrazones: synthesis of alkene-functionalized oxindoles》. The information in the text is summarized as follows:
A palladium-catalyzed cascade reaction of alkene-tethered carbamoyl chlorides 4-R-5-R1-6-R2-2-R3C(=CH2)C6HN(R4)C(O)Cl (R = H, CH3, t-Bu, OCH3, 4-F, 4-Cl, 4-NO2; R2 = H, CH3; R1R2 = -CH=CHCH=CH-; R3 = CH3, C6H5, 4-FC6H4, 4-ClC6H4, 2-FC6H4; R4 = benzyl, p-methoxybenzyl, cyclopentyl) with N-tosyl hydrazones R5HC=NNHTs (R5 = C6H5, naphthalen-1-yl, thiophen-2-yl, etc.) is described. It provided a new way to synthesize various alkene-functionalized oxindoles I bearing an all-carbon quaternary center. The olefin moieties could serve as versatile handles for further elaboration. This transformation was highly efficient and showed good functional group tolerance. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Recommanded Product: Methyltriphenylphosphonium bromide)
Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Recommanded Product: Methyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary