On January 16, 2014, Stockwell, Brent R.; Welsch, Matthew; Yang, Wan Seok published a patent.HPLC of Formula: 1019442-22-8 The title of the patent was Quinazolinone-based oncogenic-ras-selective lethal compounds and their use. And the patent contained the following:
The present invention provides compounds for treating or ameliorating the effects of a cancer having a cell that harbors an oncogenic RAS mutation, for modulating a lipoxygenase in a ferroptosis cell death pathway, and for depleting reduced glutathione (GSH) in a cell harboring an oncogenic RAS mutation are further provided. The experimental process involved the reaction of 5-Bromo-2-isopropoxyaniline(cas: 1019442-22-8).HPLC of Formula: 1019442-22-8
The Article related to antitumor quinazolinone preparation oncogenic ras mutation cancer therapy, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.HPLC of Formula: 1019442-22-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary