Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Quality Control of 585-76-2.
Zhao, Haoqiang;Xu, Jianbin;Xu, Xin;Pan, Yixiao;Yu, Zexin;Xu, Lijin;Fan, Qinghua;Walsh, Patrick J. research published 《 Rh(I)-Catalyzed Direct C6-H Arylation of 2-Pyridones with Aryl Carboxylic Acids》, the research content is summarized as follows. A Rh(I)-catalyzed C6-selective C-H arylation of 2-pyridones with inexpensive, readily available, safe and structurally diverse aryl carboxylic acids with the aid of a pyridine directing group was developed to obtain arylated pyridones I [R = H, 3-F, 4-Br, etc.; R1 = Ph, 2-ClC6H4, 2-thienyl, etc.]. This decarbonylative arylation protocol features an easy-to-handle catalytic system and was amenable to diversely substituted 2-pyridones and aryl carboxylic acids. It allowed access to a wide range of C6-arylated 2-pyridones, including those that were difficult to prepare using conventional C-H arylation processes. The method tolerates various electron-neutral, electron-rich and electron-deficient functional groups and affords the products in 41-91% yields.
Quality Control of 585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary