A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Category: bromides-buliding-blocks.
Zhang, Ming-Lu;Zhang, Xing-Long;Guo, Rui-Li;Wang, Meng-Yue;Zhao, Bao-Yin;Yang, Jin-Hui;Jia, Qiong;Wang, Yong-Qiang research published 《 Switchable, Reagent-Controlled C(sp3)-H Selective Iodination and Acetoxylation of 8-Methylquinolines》, the research content is summarized as follows. An efficient Pd-catalyzed C(sp3)-H selective iodination of 8-methylquinolines I (R = H, Ph, 4-chlorophenyl; R1 = H, Cl, Ph, etc.; R2 = H, F, Cl, Br; R3 = H, Cl, Br, I) is reported herein for the first time. Because of the versatility of organic iodides, the method offers a facile access to various C8-substituted quinolines II. By slightly switching the reaction conditions, an efficient C(sp3)-H acetoxylation of 8-methylquinolines I has also been enabled. Both approaches feature mild reaction conditions, good tolerance of functional groups, and a broad substrate scope.
Category: bromides-buliding-blocks, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary