One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid, Application of C6H6BBrO2
Yusoff, Hanis Mohd;Bala Chandran, Prasana Devi;Sayuti, Fatin Amira Binti;Kan, Su-Yin;Mohd Radzi, Siti Aisha;Yong, Fu-Siong Julius;Lee, Oon Jew;Chia, Poh Wai research published 《 Highly efficient, recyclable and alternative method of synthesizing phenols from phenylboronic acids using non-endangered metal: Samarium oxide》, the research content is summarized as follows. Oxidation of phenylboronic acid to phenol is one of the important industrial processes and it is generally employed in the plastic, explosive and drug manufacturing industries. Over the past decades, numerous efficient methods have been described for the generation of phenols from phenylboronic acids in the presence of oxidant. However, these methods suffered from various limitations, including the use of expensive, toxic reagents and sophisticated protocol to synthesize the phenols. Addnl., some of these reported literatures employed endangered metals, in which mankind is facing the risk of limited supply of these elements in 20 years’ time from now. As such, a viable alternative and green method for achieving organic synthesis is highly sought after by the chemists of today. Herein, we report for the first time a facile, efficient and alternative method in the preparation of phenols from phenylboronic acids using non-endangered metal as catalyst. In all cases, all phenols were afforded in satisfactory yields (81-96%) by employing column-free method. In the recyclability study, the Sm2O3 catalyst was found to possess good catalytic performance, even after being reused for five consecutive times (96-91%). In addition, SEM result revealed that the morphol. of the recycled Sm2O3 catalyst was well preserved after five successive uses, which indicate no observable changes occurred in the recovered catalysts. As a final note, the current method is anticipated to be useful for industries manufacturing chem. intermediates as it provides an alternative method of catalysis by using a non-endangered metal in organic transformations.
244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Application of C6H6BBrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary