A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Recommanded Product: 1-(Bromomethyl)-4-(trifluoromethyl)benzene.
Yuan, Yao;Zhang, Si-Yuan;Dong, Wu-Heng;Wu, Feng;Xie, Xiao-Min;Zhang, Zhao-Guo research published 《 Visible-Light-Induced Radical Cascade Cyclization of o-Diisocyanoarenes: Synthesis of Diethyl Benzo[a]phenazine-6,6(5H)-Dicarboxylate》, the research content is summarized as follows. A visible-light-induced radical cascade cyclization of ortho-diisocyanoarenes for the synthesis of di-Et benzo[a]phenazine-6,6(5H)-dicarboxylates has been developed. This process provides an efficient and convenient protocol for the construction of benzo[a]phenazine skeleton that widely present in biol. active mols. and pharmaceuticals. The reaction takes place under mild conditions and the products are obtained in moderate to excellent yields.
Recommanded Product: 1-(Bromomethyl)-4-(trifluoromethyl)benzene, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., 402-49-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary