On December 20, 2021, Wang, Qian; Tao, Quan; Dong, Hui; Ni, Chuanfa; Xie, Xiaoming; Hu, Jinbo published an article.Related Products of 2567-29-5 The title of the article was Fluorination Triggers Fluoroalkylation: Nucleophilic Perfluoro-tert-butylation with 1,1-Dibromo-2,2-bis(trifluoromethyl)ethylene (DBBF) and CsF. And the article contained the following:
Perfluoro-tert-butylation reaction has long remained a challenging task. We now report the use of 1,1-dibromo-2,2-bis(trifluoromethyl)ethylene (DBBF, I) as a practical reagent for perfluoro-tert-butylation reactions for the first time. Through a consecutive triple-fluorination process with DBBF and CsF, the (CF3)3C- species can be liberated and observed, which is able to serve as a robust nucleophilic perfluoro-tert-butylating agent for various electrophiles. The power of this synthetic protocol is evidenced by the efficient synthesis of structurally diverse perfluoro-tert-butylated mols. Multiple applications demonstrate the practicability of this method, as well as the superiority of perfluoro-tert-butylated compounds as sensitive probes. The perfluoro-tert-butylated product was successfully applied in 1H- and 19F-magnetic resonance imaging (MRI) experiment with an ultra-low field (ULF) MRI system. The experimental process involved the reaction of 4-(Bromomethyl)-1,1′-biphenyl(cas: 2567-29-5).Related Products of 2567-29-5
The Article related to electrophile fluorination fluoroalkylation dibromo bistrifluoromethylethylene magnetic resonance imaging safety, perfluoro tert butylated compound preparation, fluorination, fluoroalkylation, imaging probes, magnetic resonance imaging, perfluoro-tert-butylation and other aspects.Related Products of 2567-29-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary