On January 15, 2021, Rezaei, Mohammad Taher; Keypour, Hassan; Bayat, Mehdi; Soltani, Elham; Jamshidi, Mahdi; Gable, Robert William published an article.Category: bromides-buliding-blocks The title of the article was Synthesis of a tertiary amine by direct reductive amination of a carbonyl compound to form a scorpionate ligand; formation of Mn (II), Zn (II) and Cd (II) complexes, DFT calculations and, molecular docking studies. And the article contained the following:
A hexadentate, asym. tripodal scorpionate type ligand, [[N1-Pyridin-2-ylmethyl-N1-[2-(4-pyridine-2-ylmethyl-piperazine-1-yl)-ethyl]-ethane-1,2-diamine]] (L) was prepared To form this ligand, the direct reductive amination of a carbonyl compound by NaBH4 was used for the synthesis of tertiary amine. The complexes [MnL](ClO4)2, [CdL](ClO4)2, [ZnL](ClO4)2 also were prepared The synthesized compounds were characterized by elemental analyses, FTIR, ESI-MS and, NMR spectroscopy. An X-ray crystal structure of [MnL] (ClO4)2, shows that the coordination environment around the manganese is a distorted trigonal prism. The nature of metal-ligand bonding in the complexes was studied by Natural Bond Orbital anal., Energy Decomposition Anal. and Energy Decomposition Anal. using Natural Orbitals for Chem. Valence variation. Mol. docking was used for the biol. evaluation of the anticancer and antioxidant activities of the synthesized compounds The docking results indicated that the Cd, Mn, and Zn-complexes had the highest binding affinity (MolDock Score) for the binding sites of cytochrome P 450, myeloperoxidase, and cytochrome P 450, resp. The experimental process involved the reaction of 2-(2-Bromoethyl)isoindoline-1,3-dione(cas: 574-98-1).Category: bromides-buliding-blocks
The Article related to preparation manganese cadmium zinc scorpionate complex, crystal mol structure manganese cadmium zinc scorpionate complex, mol docking manganese cadmium zinc scorpionate complex, anticancer antioxidant activity manganese cadmium zinc scorpionate complex and other aspects.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary