On June 27, 2022, Huang, Ming-Yao; Zhao, Yu-Tao; Zhang, Cheng-Da; Zhu, Shou-Fei published an article.Recommanded Product: 4-(Bromomethyl)-1,1′-biphenyl The title of the article was Highly Regio-, Stereo-, and Enantioselective Copper-Catalyzed B-H Bond Insertion of α-Silylcarbenes: Efficient Access to Chiral Allylic gem-Silylboranes. And the article contained the following:
Herein, we report the development of a method for highly regio-, stereo-, and enantioselective B-H bond insertion reactions of α-silylcarbenes generated from 1-silylcyclopropenes in the presence of a chiral copper(I)/bisoxazoline catalyst for the construction of chiral γ,γ-disubstituted allylic gem-silylboranes, which cannot be prepared by any other known methods. This reaction is the first highly enantioselective carbene insertion reaction of α-silylcarbenes ever to be reported. The method shows general applicability for various 3,3-disubstituted silylcyclopropenes and exclusively affords E-products. The novel chiral γ,γ-disubstituted allylic gem-silylborane products are versatile allylic bimetallic reagents with high stability and have great synthetic potential, especially for the construction of complex mols. with continuous chiral centers. The experimental process involved the reaction of 4-(Bromomethyl)-1,1′-biphenyl(cas: 2567-29-5).Recommanded Product: 4-(Bromomethyl)-1,1′-biphenyl
The Article related to regioselective stereoselective enantioselective copper catalyst insertion silylcarbene mechanism, crystal structure mol allylic silyl borane preparation chiral, asymmetric catalysis, b−h bond insertion, carbenes, copper catalysis, cyclopropenes and other aspects.Recommanded Product: 4-(Bromomethyl)-1,1′-biphenyl
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary