On January 17, 2020, Gonzalez-Rodriguez, Jorge; Soto, Martin; Soengas, Raquel G.; Rodriguez-Solla, Humberto published an article.Category: bromides-buliding-blocks The title of the article was SmI2-promoted cross coupling reaction of N-2-bromoethylphthalimide and carbonyl compounds: Synthesis of α-aryl-α’-hydroxy ketones. And the article contained the following:
In this paper, the SmI2-mediated carbonyl-imide reductive cross coupling between N-2-bromoethylphthalimide and different aldehydes and ketones in the presence of anhydrous catalytic NiI2 was disclosed. This methodol. provided an effective tool to prepare α-aryl-α’-hydroxy ketones I [R1 = n-C7H15, 4-ClC6H4, C6H4CH=CH, etc; R1 = R2 = Et; R1R2 = (CH2)4, (CH2)5] under mild conditions which could be applied to various functionalized, aliphatic and aromatic aldehydes and ketones. The experimental process involved the reaction of 2-(2-Bromoethyl)isoindoline-1,3-dione(cas: 574-98-1).Category: bromides-buliding-blocks
The Article related to aryl alpha hydroxy ketone preparation chemoselective, bromoethylphthalimide aldehyde reductive cross coupling samarium iodide mediated, ketone bromoethylphthalimide reductive cross coupling samarium iodide mediated and other aspects.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary