On September 2, 2005, Chow, Hak-Fun; Low, Kam-Hung; Wong, King Y. published an article.Safety of 2-Bromo-4-(bromomethyl)-1-methylbenzene The title of the article was An improved method for the regiospecific synthesis of polysubstituted [2.2]paracyclophanes. And the article contained the following:
4,16-Disubstituted, 4,7,12,15-tetrasubstituted, 4,8,12,16-tetrasubstituted and 4,5,7,8,12,13,15,16-octasubstituted [2.2]paracyclophanes can be prepared in significantly improved yields and excellent regiospecificities via the Winberg 1,6-elimination-dimerization reaction from substituted (4-methylbenzyl)trimethylammonium hydroxides. Using 2-chlorophenothiazine instead of phenothiazine as a polymerization inhibitor results in a doubling of product yields. The crystal structures of two of the products are available online. The experimental process involved the reaction of 2-Bromo-4-(bromomethyl)-1-methylbenzene(cas: 259231-26-0).Safety of 2-Bromo-4-(bromomethyl)-1-methylbenzene
The Article related to paracyclophane preparation crystal structure, bromoparacyclophane preparation crystal structure, methylbenzylmethylammonium hydroxide preparation winberg elimination dimerization and other aspects.Safety of 2-Bromo-4-(bromomethyl)-1-methylbenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary