Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 90-59-5, formula is C7H4Br2O2, The most pervasive is the naturally produced bromomethane. Safety of 3,5-Dibromo-2-hydroxybenzaldehyde
Wu, Qiong;Huang, Meifen;Li, Tianyu;Jiao, Liang;Tu, Yujiao;Xu, Xindi;Ma, Xun;Tian, Hui;Qiao, Yongfeng research published 《 Crystal and electronic structure of poly-halogenated lanthanide Schiff base complex: Insights into halogen bond from structural and theoretical analysis》, the research content is summarized as follows. With the aim to explore the electronic structure and the influence of halogen bonds to the supramol. networks of lanthanide Schiff base complexes, halogenated salen-type Schiff-base and cerium nitrate were chosen as starting materials and isolated a new salen-type cerium(IV) complex [CeIV(3,5Br-salpn)2] (1) where 3,5Br-salpn = N,N’-bis(3,5-bromo salicylidene)-1,3-diaminopropane. The complex was investigated in the solid state by single-crystal X-ray diffraction. Structural anal. reveal the substitutional halogen atoms play an important role in tuning the mol. structure and supramol. networks. The electronic structure of halogen bonds was confirmed by theor. calculation, which uncovered an interesting phenomenon that the σ-hole of bromine atoms of different substituents present quite different mol. electrostatic surface potential (5-Br: Vmax = 6.8 kcal/mol and 3-Br: Vmax = 13.2 kcal/mol). Hirshfeld surface anal. showed that bromine atoms involved intermol. contacts donate 56.6% contribution of all the interactions, indicating the significant role of bromine atoms in crystal structures. Addnl., fluorescence experiments proved that the halogenated ligand has an important influence on the fluorescence behavior of the complex.
Safety of 3,5-Dibromo-2-hydroxybenzaldehyde, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.
3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.
3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).
3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary