A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Organobromine compounds have fallen under increased scrutiny for their environmental impact., SDS of cas: 2576-47-8.
Wei, Lina;Zhao, Jing;Meng, Yonghong;Guo, Yurong;Luo, Cangxue research published 《 Antibacterial activity, safety and preservative effect of aminoethyl-phloretin on the quality parameters of salmon fillets》, the research content is summarized as follows. Aminoethyl-phloretin (AEP), a novel water-soluble phloretin derivative, was synthesized from phloretin and 2-bromine ethylamine. Its antibacterial activity, safety, and preservative effect on salmon were studied. The structure of AEP was verified with UV, IR, ESI-MS and 1H NMR, 13C NMR spectroscopy. HPLC anal. showed that the solubility of AEP was 430 times higher than that of phloretin. AEP exhibited a wide range of antibacterial activity on both Gram-pos. and Gram-neg. bacteria. The results of an acute oral-toxicity test in Kunming mice and a 30-days feeding subacute toxicity test on Sprague Dawley rats demonstrated that AEP was actually non-toxic. AEP also demonstated good preservative effects on salmon fish: the color, odor, taste and cooking method can maintain high-quality characteristics for 4 days; the level of fat oxidation and biogenic amines were reduced by 3.35 times and 10 times, resp.; the total bacterial and Pseudomonas spp. counts could be suppressed by 2 logarithms and 1.5 logarithms, resp., following treatment with 4 mg/mL of AEP. Thus, AEP significantly improved the solubility of phloretin, expanding its application scope and making it a promising preservative in the food industry.
2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., SDS of cas: 2576-47-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary