Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Organic compounds having carbon bonded to bromine are called organic bromides. COA of Formula: C7H5BrO2.
Wang, Xiaochen;Zhu, Binbing;Liu, Yuxiu;Wang, Qingmin research published 《 Combined Photoredox and Carbene Catalysis for the Synthesis of α-Amino Ketones from Carboxylic Acids》, the research content is summarized as follows. Herein, a mild, operationally simple method for direct acylation of α-amino C(sp3)-H bonds from carboxylic acids RC(O)OH (R = cyclopropyl, Ph, 2-chlorophenyl, etc.) via the merger of carbene and photoredox catalysis was reported. Specifically, cross-coupling reactions between a wide range of carboxylic acids, a class of feedstock chems., and readily available N-alkyl anilines R1CH2N(R2)R3 (R1 = H; R2 = Me; R1R2 = -(CH2)3-, -(CH2OCH2CH2)-; R3 = Ph, 4-bromophenyl, pyridin-2-yl, etc.) and 1-phenyl-2,3-dihydro-1H-indole by means of single-electron N-heterocyclic carbene catalysis combined with photocatalysis provided access to structurally diverse α-amino ketones RC(O)CH(R1)N(R2)R3 and (1-phenylindolin-2-yl)(p-tolyl)methanone. The method features a broad substrate scope and is compatible with a wide array of functional groups. To demonstrate the potential applications of the method, one of the α-amino ketone products was subjected to further transformations.
585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , COA of Formula: C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary