Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 2576-47-8, formula is C2H7Br2N, The most pervasive is the naturally produced bromomethane. Synthetic Route of 2576-47-8
Wang, Hao;Gao, Yihang;Jia, Xuhong;Liu, Quanyi research published 《 Properties and mechanism of a poly(ionic liquid) inhibitor contained bi-functional groups for bentonite hydration》, the research content is summarized as follows. Present polymer inhibitors depend on a major inhibitory group to restrain bentonite hydration, and monomer design is concerned to improve the inhibition and stability through complex copolymerization Conveniently, a homopolymer (PIL-NH2) that contained primary amine and cationic imidazolium as bi-functional groups was proposed, aiming to provide two synergistic inhibitory modes. Comprehensive methods were conducted to characterize the chem. structure and inhibitory performance of PIL-NH2. The ζ potential absolute value of bentonite suspension was decreased by PIL-NH2 from 28.7-33.3 mV to 4-7 mV, and the increment of bentonite particle size d50 was observable from 1.83892μm to over 200μm. With water squeezed out, the lattice spacing d001 of hydrated bentonite was reduced from 1.9070 to 1.2683 nm due to PIL-NH2 intercalation. The ESEM images revealed that inhibited bentonite showed a tight structure with classical dehydration phenomenon, and the hydrogen bond between PIL-NH2 and bentonite was further confirmed according to the FT-IR result. In mechanism anal., the electrostatic attraction and hydrogen bond existed simultaneously for PIL-NH2 to adsorb bentonite. The two adsorption modes from bi-functional groups were synergistic to improve inhibition remarkably. PIL-NH2 maintained high performance during the whole hydration process, including crystalline hydration, osmotic hydration, and hydrated dispersion.
2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., Synthetic Route of 2576-47-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary