Month: October 2022

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, Quality Control of 629-04-9

Sydam, Rambabu;Ojha, Manoranjan;Deepa, Melepurath research published 《 Ionic additive in an ionogel for a large area long lived high contrast electrochromic device》, the research content is summarized as follows. Heptyl viologen (HV) based electrochromic devices (ECD) suffer from poor write-erase efficiencies and become permanently colored after a few redox switches, thus limiting their use as electrochromic windows or mirrors. This formidable issue is addressed by incorporating an ionic additive: a disodium salt of ethylenediamine tetra-acetic acid (EDTA), in the ionogel electrolyte. EDTA, via electrostatic interactions, binds to the HV+bul radical cation and prevents its’ further reduction to the undesirable pale colored neutral HV0, by wedging in-between the moieties and inhibiting their undesirable stacking. A large area HV/EDTA in gel/Prussian blue (PB) ECDs of ∼8 cm x 6 cm dimensions outperforms the HV/gel/PB ECD which is evidenced in the enhanced transmission modulation (ΔTmax: 73.1% at 606 nm), coloration efficiency (η: 346.2 cm2 C-1) and superior chromaticity coordinates (colored: L*,a,b: 40, 10, -65) compared to lower magnitudes of 69.2%, 270.3 cm2 C-1 and (L*,a,b: 50.3, 8, -48.5) resp. When evaluated as a mirror, HV/EDTA in gel/PB ECD shows a reflectance modulation of ∼65% which does not alter significantly, even at -10°C or at +60°C, ratifying its thermal robustness. The HV/EDTA in gel/PB ECD shows color and bleach times of 16 and 35 s, retains ∼93% of its’ initial contrast after 104 cycles and after aging for 2 years, continues to deliver a transmission modulation of 68%. This study successfully demonstrates a cost effective, easily implementable, scaled-up HV/EDTA in gel/PB based long-lived durable ECD for energy efficient smart window and rearview mirror applications.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Quality Control of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5445-17-0, formula is C4H7BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: Methyl 2-bromopropanoate

Swisher, Nicholas A.;Corbin, Daniel A.;Miyake, Garret M. research published 《 Synthesis, Characterization, and Reactivity of N-Alkyl Phenoxazines in Organocatalyzed Atom Transfer Radical Polymerization》, the research content is summarized as follows. Core-modified N-alkyl phenoxazines were synthesized and evaluated as photoredox catalysts (PCs) in organocatalyzed atom transfer radical polymerization (O-ATRP). Each PC was characterized and found to strongly absorb UVA and visible light, undergo reversible oxidation to radical cation species, and exhibit high quantum yields of fluorescence (F_f > 77%). PCs found to exhibit intramol. charge transfer in their excited state were capable of the controlled synthesis of poly(Me methacrylate) with good mol. weight control (I* ~100%) and moderately low dispersity (D < 1.30).

Recommanded Product: Methyl 2-bromopropanoate, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Name: 2-Bromoethylamine hydrobromide.

Svec, Pavel;Petrov, Oleg V.;Lang, Jan;Stepnicka, Petr;Groborz, Ondrej;Dunlop, David;Blahut, Jan;Kolouchova, Kristyna;Loukotova, Lenka;Sedlacek, Ondrej;Heizer, Tomas;Tosner, Zdenek;Slouf, Miroslav;Benes, Hynek;Hoogenboom, Richard;Hruby, Martin research published 《 Fluorinated Ferrocene Moieties as a Platform for Redox-Responsive Polymer ¹⁹F MRI Theranostics》, the research content is summarized as follows. Fluorine-19 magnetic resonance imaging (¹⁹F MRI) stands out as a powerful tool for noninvasive diagnostics. In particular, polymer-based ¹⁹F MRI tracers offer tunable physicochem. properties, including solubility and thermoresponsiveness, and enhanced ¹⁹F MRI performance. However, these tracers do not detectably respond to redox changes or do so in only one redox state, thereby preventing potential applications to reactive oxygen species (ROS) bioimaging. Herein, we report the first amphiphilic redox-responsive, poly(2-oxazoline)-based polymers bearing fluorinated ferrocene moieties. Their hydrophobicity and redox responsiveness were tailored by changing the monomer ratio and substitution pattern of the fluorinated ferrocene units. Converting the diamagnetic fluorinated ferrocene moieties into paramagnetic ferrocenium markedly changed the chem. shift and relaxation times of the ¹⁹F nuclei distinguishable by ¹⁹F MRI. In turn, the statistical-diblock copolymers formed nanoparticles that disassemble upon oxidation, with no toxicity to cultured cells. Therefore, these polymers may be used to release lipophilic drugs in ROS-rich malignancies.

Name: 2-Bromoethylamine hydrobromide, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Reference of 20469-65-2.

Sunnapu, Ranganayakulu;Rajendar, Goreti research published 《 A Concise Stereoselective Total Synthesis of Methoxyl Citreochlorols and Their Structural Revisions》, the research content is summarized as follows. A concise, stereoselective and protecting group free approaches for the total synthesis of (-)-(2S,4R)- and (+)-(2R,4S)-3′-methoxyl citreochlorols, e.g., I, and their stereoisomers are demonstrated. All four stereoisomers were synthesized to establish the absolute stereochem. of the reported structures and the structures were revised accordingly. The approach involves chelation controlled regioselective reduction of a diester, silyl iodide promoted ring-opening iodo esterification of lactones, highly chemo- and regioselective ring-opening of an epoxy ester, dichloromethylation of a carboxyl group, and syn- and anti-selective reduction of the resulted β-hydroxy ketone as key steps.

Reference of 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 90-59-5.

Sundaresan, Sriram;Kuhne, Irina A.;Evesson, Colin;Harris, Michelle M.;Fitzpatrick, Anthony J.;Ahmed, Ahmed;Muller-Bunz, Helge;Morgan, Grace G. research published 《 Compressed Jahn-Teller octahedra and spin quintet-triplet switching in coordinatively elastic manganese(III) complexes》, the research content is summarized as follows. Complex assembly preferences and resultant spin state choice and Jahn-Teller distortion mode in twelve Mn(III) complexes of varying nuclearity with Schiff base chelate ligands of different sizes are compared. Mononuclear complexes [Mn(5-F-Sal₂323)]OTf (1), [Mn(5-F-Sal₂323)]ClO₄ (2) and [Mn(5-F-Sal₂323)]NO₃, (3) with the 8-carbon R-Sal₂323 chelate type show rare axial compression at room temperature and complexes (2) and (3) also show reversible thermal spin state switching from spin quintet to triplet states on cooling. The prevalence of atypical axial compression is further probed by single crystal diffraction studies on high spin mononuclear complexes (4)-(7) with the longer 9-carbon R-Sal₂333 chelate series using [Mn(3-OEt-Sal₂333)]BF₄, (4) [Mn(3,5-diOMe-Sal₂333)]BF₄·0.5PrOH, (5), [Mn(5-F-Sal₂333)]BPh₄, (6) and [Mn(5-NO₂-Sal₂333)]BPh₄, (7) as examples. Ring closure of both the 8-carbon R-Sal₂323 and longer 9-carbon R-Sal₂333 ligands was also observed yielding a ligand with a 6-membered ring in the mononuclear complex [Mn(3-OMe,5-NO₂-Sal₂333^6R)]·0.07MeOH·0.93MeCN (8) in contrast to a protonated 5-membered ring in the dimeric complex [Mn₂(5-Cl-Sal₂323^H5R)₂](ClO₄)₂·1.85EtOH·0.33MeCN, (9) with the R-Sal₂323 chelate type. Finally comparison of the assembly modes of Mn(III) complexes of the 8-carbon R-Sal₂323 and 9-carbon R-Sal₂333 series with those of the shorter 7-carbon R-Sal₂322 ligand series reveal that the mononuclear assembly mode is not favored with the smaller chelate. Instead three dimeric or cluster complexes with rearranged ligands were recovered in low yield. The structures of these complexes [Mn₂(5-NO₂-Sal₂322^5R)₂]·2BuOH, (10), [Mn₂(3,5-diBr-Sal₂322^5R)(3,5-diBr-Sal)₃]·0.7EtOH·2.61MeCN, (11) and [Mn₂Na(3-NO₂,5-OMe-Sal₂322^5R)]ClO₄·0.5MeCN (12) are reported and compared with examples with the longer chain R-Sal₂323 and R-Sal₂333 chelate ligands.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., Related Products of 90-59-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Formula: C9H9BrO3.

Sunagatullina, Alisa S.;Lutter, Ferdinand H.;Knochel, Paul research published 《 Preparation of Primary and Secondary Dialkylmagnesiums by a Radical I/Mg-Exchange Reaction Using sBu₂Mg in Toluene》, the research content is summarized as follows. The treatment of primary or secondary alkyl iodides with sBu₂Mg in toluene (25-40°, 2-4 h) provided dialkylmagnesiums that underwent various reactions with aldehydes, ketones, acid chlorides or allylic bromides. 3-Substituted secondary cyclohexyl iodides led to all-cis-3-cyclohexylmagnesium reagents under these exchange conditions in a highly stereoconvergent manner. Enantiomerically enriched 3-silyloxy-substituted secondary alkyl iodides gave after an exchange reaction with sBu₂Mg stereodefined dialkylmagnesiums that after quenching with various electrophiles furnished various 1,3-stereodefined products including homo-aldol products (99% dr and 98% ee). Mechanistic studies confirmed a radical pathway for these new iodine/magnesium-exchange reactions.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Formula: C9H9BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C7H8BrN.

Sun, Zhaozhao;Huang, Huawen;Wang, Qiaolin;Huang, Chunyan;Mao, Guojiang;Deng, Guo-Jun research published 《 Visible light-mediated radical-cascade addition/cyclization of arylacrylamides with aldehydes to form quaternary oxindoles at room temperature》, the research content is summarized as follows. A visible-light-mediated oxidative cyclization of N-arylacrylamides by a radical cascade with readily available aliphatic or aromatic aldehydes was achieved. This transformation provided an operationally convenient, mild, and efficient access to various alkyl-substituted or acyl-substituted oxindoles at room temperature under metal-free conditions. This protocol featured good functional group tolerance and high chemoselectivity with general yields ranging from moderate to good. Mechanistic studies reveal that the bromo radical probably played a promotional role in the formation of the acyl radical via HAT.

Application of C7H8BrN, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 20469-65-2, formula is C8H9BrO2, The most pervasive is the naturally produced bromomethane. Computed Properties of 20469-65-2

Sun, Yuan-Li;Tan, Fang-Fang;Hu, Rong-Gui;Hu, Chun-Hong;Li, Yang research published 《 Visible-Light Photoredox-Catalyzed Hydrodecarboxylation and Deuterodecarboxylation of Fatty Acids》, the research content is summarized as follows. An efficient visible-light photoreodox-catalyzed hydrodecarboxylation and deuterodecarboxylation of fatty acids for alkanes and deuterium alkanes was developed. The key to the efficient transformation should attribute to the co-catalysis of the suitable methoxy substituted acridine photocatalyst and the hydrogen atom transfer catalyst 4′,4′-dimethyl diphenyldisulfane, possibly via facilitating of quenching the active alkyl radicals to overcome the competitive homocoupling products, olefins via the disproportionation, cracking products via the C-C bond β-scission.

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Computed Properties of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 1575-37-7.

Sun, Xiaohua;Feng, Lijun;Sun, Chuance;Kang, Congmin research published 《 Synthesis of Quinoxaline Derivatives as Intermediates to Obtain Erdafitinib》, the research content is summarized as follows. In this work, quinoxaline derivative 7-bromo-2-(1-methyl-1H-pyrazol-4-yl)quinoxaline, which is an essential intermediate to obtain drug erdafitinib, has been synthesized in reasonably good yield using 4-bromobenzene-1,2-diamine and 2-bromo-1-(1-methyl-1H-pyrazol-4-yl)ethan-1-one as raw materials, triethylene diamine (DABCO) as catalyst, and THF as solvent. To the best of authors’ knowledge, this is the first time 7-bromo-2-(1-methyl-1H-pyrazol-4-yl)quinoxaline has been acquired by the proposed method.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Synthetic Route of 1575-37-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5445-17-0, formula is C4H7BrO2, The most pervasive is the naturally produced bromomethane. COA of Formula: C4H7BrO2

Sun, Xiang;Ritter, Tobias research published 《 Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids》, the research content is summarized as follows. Polyfluoroarenes are useful building blocks in several areas such as drug discovery, materials, and crop protection. Herein, we report the first polyfluoroarylation of aliphatic carboxylic acids via photoredox decarboxylation. The method proceeds with broad substrate scope and high functional group tolerance. Moreover, small complex mols. such as natural products and drugs can be modified by late-stage modification.

COA of Formula: C4H7BrO2, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary