Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Reference of 4224-70-8.
Tahir, M. Nazir;Harati, Masoud;Nyayachavadi, Audithya;Rezapour, Mehdi;Eichhorn, S. Holger;Rondeau-Gagne, Simon research published 《 Intrinsically Porous Polydiacetylene from a Functionalized Bowl-Shaped Hexaphenoxycyclotriphosphazene Derivative》, the research content is summarized as follows. Intrinsic porosity in polymeric materials arises from the formation of a continuous network of interconnected voids and is a direct consequence of the shape and rigidity of the mol. building blocks. To obtain well-defined pores with narrow size distributions, the polymerization of rigid and sterically hindered monomers must not interfere with the pore formation and should avoid the use of additives that may occupy voids. Polydiacetylenes can be generated by the topochem. polymerization of diacetylene-bearing mols. favorably arranged in crystals, gels, thin films, or vesicles. Polydiacetylene formation in amorphous materials has been sparsely studied because higher-order self-assembled structures are assumed to be required for the topochem. polymerization of 1,3-butadiyne to occur. In this study, a bulky hexachlorocyclotriphosphazene core (N3P3Cl6) was functionalized with six diacetylene-containing alkyl chains and successfully converted to an intrinsically porous multifunctional polydiacetylene. The successful formation of the polydiacetylene was confirmed by Raman spectroscopy, and the porous structure of the resulting materials was verified by X-ray diffraction and Brunauer-Emmett-Teller surface area measurements. This investigation revealed a significant change in the porous structure after polymerization, leading to a 5-fold increase in sp. surface area. Overall, the topochem. polymerization of diacetylenes is a promising strategy for the preparation of functional materials, which is shown to be compatible with rather amorphous phases of bulky mols. The results obtained from this investigation give access to a range of porous polydiacetylene materials for potential applications in organic electronics, gas adsorption, and other related fields.
4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Reference of 4224-70-8
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary