Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Reference of 90-59-5.
Stangier, Maximilian;Messinis, Antonis M.;Oliveira, Joao C. A.;Yu, Hao;Ackermann, Lutz research published 《 Rhodaelectro-catalyzed access to chromones via formyl C-H activation towards peptide electro-labeling》, the research content is summarized as follows. Herein, a strategy for the sustainable assembly of chromones I (R = H, Cl, ethenyl; R1 = H, OMe, Ph, Br, etc.; R2 = H, Me, diethylaminyl, F, etc.; R1R2 = 7-oxo-dodecahydro-1H-cyclopenta[a]naphthalene-3,4-bis(ylium);R3 = H, Cl, OMe, Me, t-Bu, Br; R2R3 = -(CH=CH-CH=CH)-; R4 = Me, Ph, naphthalen-2-yl, (morpholin-4-yl)carbonyl, etc.; R5 = t-Bu, Ph, naphthalen-1-yl, 3,5-dimethylphenyl, etc.; R4R5 = 2-(benzen-2-yl-1-yl)benzen-1-yl, 1-(naphthalen-2-yl-1-yl)naphthalen-2-yl) via electro-formyl C-H activation is presented. The rational design of the rhodaelectro-catalysis is guided by detailed mechanistic insights and provides versatile access to tyrosine-based fluorogenic peptidomimetics.
Reference of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.
3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.
3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).
3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary