Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Application of C2H7Br2N.
Song, Lijun;Zhang, Haijuan;Chen, Jia;Li, Zhan;Guan, Ming;Qiu, Hongdeng research published 《 Imidazolium ionic liquids-derived carbon dots-modified silica stationary phase for hydrophilic interaction chromatography》, the research content is summarized as follows. Imidazolium ionic liquids-derived carbon dots (ImCDs) were successfully synthesized and bonded on the surface of spherical porous silica as a new stationary phase (Sil-ImCDs) for hydrophilic interaction chromatog. (HILIC). First, the ImCDs were synthesized by the reaction of amino ionic liquids with citric acid, and then they were grafted onto the surface of aminopropyl-modified silica. A series of characterizations including IR spectra, elemental anal. and laser confocal microscope proved that the preparation was successful. The Sil-ImCDs had good separation efficiency in the separation of bases, nucleosides, amino acids, saccharides and ginsenosides. Sil-ImCDs has better hydrophilic chromatog. performance compared with methylimidazole-modified silica and aminopropyl-modified silica. It may be due to the rich functional group which is available after the formation of carbon dots from imidazolium ionic liquids and citric acid.
2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., Application of C2H7Br2N
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary