Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Formula: C5H7BrO3
Soleimani Amiri, Somayeh;Hossaini, Zinatossadat;Azizi, Zahra research published 《 Synthesis and investigation of antioxidant and antimicrobial activity of new pyrazinopyrroloazepine derivatives using Fe3O4/CuO/ZnO@MWCNT MNCs as organometallic nanocatalyst by new MCRs》, the research content is summarized as follows. In this study, authors synthesized pyrazinopyrroloazepine derivatives I (R = 4-CH3OC6H4, 4-CH3C6H4, 4-O2NC6H4, etc.; R1 = CO2Me, CO2Et, H; R2 = CO2Me, CO2Et; R3 = H, Me, NO2, Cl) in high yields using multicomponent reactions of isatoic anhydride, N-methylimidazole, alkyl bromides, activated acetylenic compounds, Et glycinate and Me aziridine in the presence of Fe3O4/CuO/ZnO@MWCNT as a high performance catalyst in water at room temperature The Fe3O4/CuO/ZnO@MWCNT synthesizes using Petasites hybridus rhizome water extract as a green media and moderate base. As well the catalyst show a good improvement in the yield of the product and displayed significant reusable activity. Investigation of antioxidant ability of synthesized compounds using radical trapping of diphenyl-picrylhydrazine (DPPH) and ferric reduction power experiment is another purpose in this research. Because of having two NH groups in the synthesized compounds, these compounds shown the good antioxidant activity relative two standards Compound I (R = 4-CH3C6H4; R’ = H; R” = Me; X = H) was shown excellent antioxidant activity. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on gram-pos. and gram-neg. bacteria. The pyrazinopyrroloazepines I (R = 4-CH3OC6H4, R1 = R2 = CO2Me, R3 = H; R = 4-CH3OC6H4, R1 = H, R2 = CO2Me, R3 = Me; R = 4-CH3C6H4, R1 = H,CO2Me, R2 = CO2Me, R3 = H) have the maximum effect on E. coli compared with gram-pos. and gram-neg. bacteria because of good inhibition zone diameter
Formula: C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary