Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Formula: C5H7BrO3
Sharafian, Shirin;Hossaini, Zinatossadat;Rostami-Charati, Faramarz;Khalilzadeh, Mohammad A. research published 《 Ultrasound-promoted Green Synthesis of Pyrido[2,1-a]isoquinoline Derivatives and Studies on their Antioxidant Activity》, the research content is summarized as follows. In this work, synthesis of pyrido[2,1-a]isoquinolines I (R = EtO2C, 4-MeOC6H4, 4-MeC6H4, 4-BrC6H4, 4-O2NC6H4; R1 = H, MeO2C, EtO2C; R2 = Me, Et) via multicomponent reaction of phthalaldehyde, methylamine, α-bromo carbonyls RC(O)CH2Br, activated acetylenic compounds R1CCCO2R2 and triphenylphosphine in water under ultrasonic irradiation conditions at room temperature in excellent yields in short time was performed. The subsequent Diels-Alder reaction of pyrido[2,1-a]isoquinolines I (R = EtO2C, 4-MeOC6H4, 4-MeC6H4, 4-O2NC6H4; R1 = MeO2C, EtO2C; R2 = Me, Et) with activated acetylenic compounds R1CCCO2R2 afforded the corresponding adducts II. Adducts II were also prepared directly from phthalaldehyde, α-bromo carbonyls and acetylenic compounds without isolation of the intermediate pyrido[2,1-a]isoquinolines. Also, the antioxidant activities of four compounds I were evaluated by DPPH radical scavenging and ferric reducing power anal. (FRAP). The compound I (R = EtO2C; R1 = MeO2C; R2 = Me) exhibited excellent DPPH radical scavenging activity and FRAP compared to synthetic antioxidants BHT and TBHQ. The chief benefits of the method are high atom economy, green reaction conditions, higher yield, shorter reaction times, and easy work-up, which agree with some principles of green chem.
Formula: C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary