A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Category: bromides-buliding-blocks.
Shaik, Mahammad Sadik;Nadiveedhi, Maheshwara Reddy;Gundluru, Mohan;Narreddy, Ananda Kumar Reddy;Thathireddy, Krishna Reddy;Ramakrishna, Ranjani;Cirandur, Suresh Reddy research published 《 2-Amino-3-cyano-4H-chromene-4-ylphosphonates as potential antiviral agents: Synthesis, in ovo and in silico approach》, the research content is summarized as follows. A simplistic synthetic procedure for the synthesis of structurally diversified 2-amino-3-cyano-4H-chromene-4-ylphosphonates were developed by the treatment of substituted salicylaldehydes, malononitrile, and dialkyl phosphite in presence of Cu(OAc)2 catalyst at room temperature and neat conditions. The synthesized compounds were tested for their antiviral assay. Among all, the compounds three have shown good in ovo antiviral activity against New castle disease virus (NDV) at a concentration of 150μg/mL. The remarkable reduction in NDV virus population in embryos treated with title compounds in a dose dependent manner, indicated that the synthesized compounds are extreme by toxic to the NDV virus. The title compounds were also docked against hemagglutinin neuraminidase enzyme and the more bioactive compound showed highest docking score than the standard antiviral drug taribavirin while two compounds have the same docking score as that of the standard
90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.
3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.
3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).
3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary