Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Electric Literature of 70-23-5.
Shafaei, Faezeh;Najar, Asef H. research published 《 Green synthesis of 4H-pyran derivatives using Fe3O4-MNPs as efficient nanocatalyst: study of antioxidant activity》, the research content is summarized as follows. A series of dialkyl 4-(oxo-alkoxy/aryl)-5-oxo-4,5-dihydroindeno[1,2-b]pyran-2,3-dicarboxylates I [R = CO2Et, 4-MeC6H4, 4-BrC6H4, etc.; R1 = Me, Et] was synthesized via a multicomponent reaction of ninhydrin, α-haloketones, dialkyl acetylenedicarboxylates and triphenylphosphine in the presence of iron oxide magnetic nanoparticles (Fe3O4-MNPs) as efficient nanocatalyst in ethanol at room temperature The biosynthesis of Fe3O4-MNPs was achieved using Clover Leaf water extract In addition, antioxidant activity was examined for some of the compounds I [R = CO2Et, 4-MeC6H4, 4-MeOC6H4, 4-O2NC6H4; R1 = Me, Et] employing DPPH radical scavenging and ferric reduction activity potential (FRAP) experiment and compared results with synthetic antioxidants (TBHQ and BHT). Compound I [R = CO2Et; R1 = Et] showed excellent radical trapping activity and good reducing activity relative to standards (BHT and TBHQ). Some advantages of this procedure were easiness of reaction workup and seperation of products by simply filtration. Fe3O4-MNPs displayed a good improvement in the yield of the product and showed significant reusable activity.
Electric Literature of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary