Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Electric Literature of 90-59-5.
Rudbari, Hadi Amiri;Saadati, Arezoo;Aryaeifar, Mahnaz;Blacque, Olivier;Correia, Isabel;Islam, Mohammad Khairul;Woschko, Dennis;Janiak, Christoph;Enamullah, Mohammed research published 《 Pseudotetrahedral Zn(II)-(R or S)-dihalogen-salicylaldiminato complexes with Λ- or Δ-chirality induction at-metal》, the research content is summarized as follows. Reactions of enantiopure (S or R)-N-1-(phenyl)ethyl-2,4-X1,X2-salicylaldimine (S-H or R-H; X1, X2 = dihalogen) with Zn(II)-nitrate give bis[(S or R)-N-1-(phenyl)ethyl-2,4-X1,X2-salicylaldiminato-κ2N,O]-Zn(II), (Δ-ZnS or Λ-ZnR) with Δ/Λ-chirality induction at-metal in the C2-sym. mols. EI-mass spectra show parent ion peaks. X-ray structures indicate that two phenolate-O and two imine-N atoms from two mols. of the Schiff bases coordinate to the Zn(II) ion in a pseudotetrahedral geometry. Structural analyses give evidence that the S- or R-ligand chirality gives only one diastereomer Δ-ZnS or Λ-ZnR in an enantiopure crystal. Gas-phase optimized structures suggest that the Δ-ZnS or Λ-ZnR diastereomers are slightly more stable than Λ-ZnS or Δ-ZnR by 1-2 kcal mol-1. The intramol. interactions were analyzed with the Independent Gradient Model (IGM) using the program Multiwfn on the optimized structures and also indicate the diastereomeric preference of Δ-ZnS1 over Λ-ZnS1 (or Λ-ZnR1 over Δ-ZnR1). Variable time and temperature 1H NMR spectra support the presence of only one diastereomer Λ-ZnR or Δ-ZnS in the bulk samples, backed by the simulated spectra which exhibit no diastereomerization in solution In contrast, the reported Zn(II)-(R or S)-salicylaldiminato/naphthaldiminato complexes show a diastereomeric mixture of both Δ- and Λ-forms and a Δ ⇄ Λ equilibrium in solution Electronic CD (ECD) spectra in solution display expected mirror-image relations for the (S or R)-Schiff base ligands and the (S or R)-ligated complexes. Combined analyses of exptl. and simulated ECD spectra further support the notion of diastereomeric excess of Δ-ZnS or Λ-ZnR in solution The overall results thus suggest the preservation of chirality at-Zn induced by S- or R-ligands in a solid or solution Supramol. packing analyses explore different kinds of intermol. interactions with the strongest one for X···O. Only the halogen atom in the para position is involved in these interactions with Br···O > Cl···O. Hirshfeld surface analyses also support these interactions between two mols. at a distance shorter than the sum of the van der Wall radii. Comparison of the exptl. and simulated PXRD patterns from the single-crystal x-ray structures shows a good matching and confirms the phase purity of the bulk samples.
Electric Literature of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.
3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.
3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).
3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary