Organic compounds having carbon bonded to bromine are called organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Category: bromides-buliding-blocks.
Reason, Thomas E.;Goka, Benjamin;Krause, Jeanette A.;Fionah, Abelline K.;Zahran, Elsayed M.;Rayat, Sundeep research published 《 Cu2O nanoparticle-catalyzed synthesis of diaryl tetrazolones and investigation of their solid-state properties》, the research content is summarized as follows. An efficient and versatile method for the synthesis of 1,4-diaryl tetrazolones I [Ar1 = Ph, 4-MeOC6H4, 4-O2NC6H4; Ar2 = Ph, 4-FC6H4, 3-pyridyl, etc.] was reported which involved C-N coupling of aryl tetrazolones with aryl boronic acids in the presence of Cu2O nanoparticles under an oxygen atm. and DMSO as solvent. The reaction tolerated a variety of electron donating and electron withdrawing substituents on both substrates and produced the desired 1,4-diaryl tetrazolones I in moderate to good yields. In the crystal lattice, the mols. exhibited π···π stacking interactions between the adjacent layers as well as weak through-space electrostatic C-H···O interactions involved the pendant rings and tetrazolone carbonyl. The compounds I [Ar1 = 4-MeOC6H4; Ar2 = 3-MeC6H4, 3-FC6H4] differed only in the presence of one group (Me or fluoro), exhibited an identical pattern of noncovalent interactions in the solid-state. Hirshfeld surface anal. had also been performed to visualize intermol. interactions.
Category: bromides-buliding-blocks, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary