Organic compounds having carbon bonded to bromine are called organic bromides. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C2H7Br2N.
Rani, Kavita;Pandey, Upendra K.;Sengupta, Sanchita research published 《 Efficient electron transporting and panchromatic absorbing FRET cassettes based on aza-BODIPY and perylenediimide towards multiple metal FRET-Off sensing and ratiometric temperature sensing》, the research content is summarized as follows. Multichromophoric triads based on aza-BODIPY as the central chromophore and bay-substituted (tetrachloro- and tetraphenoxy-)perylenediimides (PDI) as peripheral chromophores have been designed and synthesized that are panchromatic absorbers and near IR (NIR) emitters. Both triads exhibited ~99% Forster resonance energy transfer (FRET) from the peripheral PDIs to central aza-BODIPY. The excitation energy transfer from PDI to aza-BODIPY was studied via steady state emission, fluorescence quantum yield, time resolved fluorescence emission and theor. calculations These studies revealed quant. singlet excitation energy transfer efficiencies for 1 and 2. Electrochem. studies revealed the strong electron deficient character of these triads and thus electron mobilities of these triads were measured using space charge limited current (SCLC) method. Triads 1 and 2 exhibited appreciable electron mobilities of 2.44 ± 1.70 x 10-3 cm2 V-1 s-1 and 4.00 ± 1.50 x 10-3 cm2 V-1 s-1 resp., an order of magnitude higher mobility than aza-BODIPY based small mols. reported in the literature. Leveraging upon the dual emission behavior of these triads, ratiometric FRET sensing as well as ratiometric temperature sensing behavior were investigated via steady state absorption and fluorescence measurements. Triads 1 and 2 showed remarkable ratiometric FRET-off sensing where the addition of metals such as Co2+ and Fe3+ led to near-quant. FRET off for both the triads. Triads 1 and 2 also serve as efficient ratiometric temperature sensors with pos. temperature coefficients and small temperature sensitivities of ~0.29% °C-1 and ~0.14% °C-1 resp. that suggest the possibility of precise physiol. temperature measurements using these triads.
2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., COA of Formula: C2H7Br2N
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary