Priestley, E. Scott team published research in Journal of Medicinal Chemistry in 2022 | 70-23-5

Related Products of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Related Products of 70-23-5.

Priestley, E. Scott;Banville, Jacques;Deon, Daniel;Dube, Laurence;Gagnon, Marc;Guy, Julia;Lapointe, Philippe;Lavallee, Jean-Francois;Martel, Alain;Plamondon, Serge;Remillard, Roger;Ruediger, Edward;Tremblay, Francois;Posy, Shana L.;Guarino, Victor R.;Richter, Jeremy M.;Li, Jianqing;Gupta, Anuradha;Vetrichelvan, Muthalagu;Balapragalathan, T. J.;Mathur, Arvind;Hua, Ji;Callejo, Mario;Guay, Jocelyne;Sum, Chi Shing;Cvijic, Mary Ellen;Watson, Carol;Wong, Pancras;Yang, Jing;Bouvier, Michel;Gordon, David A.;Wexler, Ruth R.;Marinier, Anne research published 《 Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4》, the research content is summarized as follows. Herein, the optimization of a series of imidazothiadiazole PAR4 antagonists to a first-in-class clin. candidate, BMS-986120 I, and a backup clin. candidate, BMS-986141 II was described. Both compounds demonstrated excellent antithrombotic efficacy and minimal bleeding time prolongation in monkey models relative to the clin. important antiplatelet agent clopidogrel and provide a potential opportunity to improve the standard of care in the treatment of arterial thrombosis.

Related Products of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary