One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Reference of 70-23-5
Pragathi, Y. J.;Veronica, D.;Rao, M. V. Basaveswara;Raju, R. R. research published 《 Design, Synthesis, and Anticancer Activity of 1,3,4-Oxadiazole Incorporated 5-(Pyrimidin-5-yl)benzo[d]oxazole Derivatives》, the research content is summarized as follows. A novel series of 5-(pyrimidin-5-yl)benzo[d]oxazole derivatives I [R = H, 4-MeO, 3,5-di-O2N, etc.] was synthesized and the chem. structures of products were determined by 1H and 13C NMR, and mass spectra. The products I were tested for their anticancer activity against a panel of human cancer cell lines such as MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer) and A2780 (ovarian cancer) using MTT assay. Some tested compounds were demonstrated significant anticancer activity higher than that of the reference drug.
Reference of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary