Organic compounds having carbon bonded to bromine are called organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of Ethyl 3-bromo-2-oxopropanoate.
Noushin, Annataj;Sayyed-Alangi, S. Zahra;Varasteh-Moradi, Ali;Hossaini, Zinatossadat;Arshadi, Sattar research published 《 KF Impregnated Natrolite Zeolite as a New Heterogeneous Nanocatalyst Promoted One-Pot Synthesis of Benzo[1,4]-Diazepin-5-One Derivatives》, the research content is summarized as follows. In this study, KF impregnated natural natrolite zeolite nanoparticle was reported as a new and economical heterogeneous catalyst. The KF/Natrolite NPs as a high performance catalyst was employed for the preparation of a new family of substituted benzo[e][1,4]-diazepin-5-ones I (R = Et, Ph, 4-O2NC6H4, etc.; R′ = 4-BrC6H4, 4-MeOC6H4, CO2Et, etc.) using the one-pot condensation reactions of isatoic anhydride, primary amines and α-haloketones at 50 °C under solvent free condition. The some advantages of this procedure are the short time of reaction, high yields of product, easy separation of catalyst and products. Due to having benzazepine core, authors investigate antioxidant property of some synthesized compounds by diphenyl-picrylhydrazine (DPPH) radical trapping experiment It was observed that the compounds I (R = Ph; R′ = 4-BrC6H4) and I (R = Ph; R′ = 4-MeOC6H4) had good DPPH· radical scavenging.
Safety of Ethyl 3-bromo-2-oxopropanoate, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary