Organic compounds having carbon bonded to bromine are called organic bromides. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Product Details of C9H9BrO3.
Naz, Fouzia;Kanwal;Latif, Mehreen;Salar, Uzma;Khan, Khalid Mohammed;al-Rashida, Mariya;Ali, Irfan;Ali, Basharat;Taha, Muhammad;Perveen, Shahnaz research published 《 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors》, the research content is summarized as follows. The N’-benzylidene-2-((2-oxo-2H-chromen-4-yl)oxy)acetohydrazide Schiff base derivatives (E,Z)-I (R = 4-OH, benzyloxidanyl, 3,5-dimethoxy, etc.) were synthesized by following a three step reaction strategy. All mols. were assessed for urease inhibitory activity and found to possess a varying degree of inhibitory potential in the range of IC50 = 12.3 ± 0.69 to 88.8 ± 0.04μM. Amongst the active analogs, compounds (E,Z)-I (R = 3-OH) (IC50 = 16.2 ± 0.11μM), (E,Z)-I (R = benzyloxidanyl) (IC50 = 15.2 ± 0.14μM), (E,Z)-I (R = 2,3,4-trimethoxy) (IC50 = 12.3 ± 0.69μM), (E,Z)-I (R = 3,5-dimethoxy) (IC50 = 16.3 ± 0.45μM), and (E,Z)-I (R = 2-OMe) (IC50 = 17.6 ± 0.28μM) were identified as potent inhibitors compared to standard urea (IC50 = 21.5 ± 0.47μM). It is conferred from structure-activity relationship (SAR) that variation in inhibitory activity is due to different substitutions pattern on aryl ring. Moreover, mol. docking studies were carried out to understand the interactions of ligand with the active pocket of urease enzyme.
5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Product Details of C9H9BrO3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary