A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 2576-47-8.
Martyanov, Timofey P.;Ushakov, Evgeny N.;Nuriev, Vyacheslav N.;Aleksandrova, Nadezhda A.;Sazonov, Sergey K.;Vedernikov, Artem I.;Kuz’mina, Lyudmila G.;Klimenko, Lubov S.;Martyanova, Elena G.;Gromov, Sergey P. research published 《 Pseudodimeric Complexes of an (18-Crown-6)stilbene with Styryl Dyes Containing an Ammonioalkyl Group: Synthesis, Structure, and Stereospecific [2 + 2] Cross-Photocycloaddition》, the research content is summarized as follows. A new efficient method was proposed for the synthesis of (18-crown-6)stilbene; the structure of the product was confirmed by X-ray diffraction anal. In MeCN, this compound forms pseudodimeric complexes with N-(2-ammonioethyl)-4-styrylpyridinium and N-(3-ammoniopropyl)-4-styrylpyridinium diperchlorates via hydrogen bonding between the ammonium group and the crown ether oxygen atoms. The ammonioethyl derivative was synthesized for the first time. The stability constants and spectral characteristics of the complexes were measured by spectrophotometric and fluorescence titration Photoirradiation of the pseudodimeric complex of (18-crown-6)stilbene with the ammoniopropyl dye resulted in the stereospecific [2 + 2] cross-photocycloaddition reaction. The replacement of the stilbene moiety in the crown compound by a styrylpyridine moiety led to a 5-fold increase in the quantum yield of the photoprocess. The most probable cause for this effect is the presence of photoinduced electron transfer in (18-crown-6)stilbene complexes. This assumption is confirmed by fluorescence lifetime spectroscopy and d. functional theory calculations
Related Products of 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,10,15,20-tetrakis(1-methylpyridinium-4-yl)porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary