One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid, Synthetic Route of 244205-40-1
Low, Choon Heng;Buss, Joshua A.;Agapie, Theodor research published 《 Molybdenum-Mediated Coupling of Carbon Monoxide to a C3 Product on a Single Metal Site》, the research content is summarized as follows. The synthesis and characterization of naphthalenediyl-diphosphine Mo complexes are reported. A novel dicarbonyl-Mo complex 3 converts to bis(siloxy)acetylene complex 5 upon reduction and treatment with a silylelectrophile, Me3SiCl. This process shows exclusive C-C coupling distinct from the phenylene-linked analog that undergoes C-O cleavage. Further CO catenation can be engendered from 5 under mild conditions providing metallacyclobutenone complex 6, with a C3O3 organic motif derived from CO. Differences in reactivity are assigned to the nature of the arene linker, where the naphthalenediyl fragment shows a propensity for η4 binding previously not observed for phenylene. Consistent with this hypothesis, a Mo precursor with a 1,3-cyclohexadienediyl-based linker was prepared In agreement, this species also shows exclusive formation of a bis(siloxy)acetylene complex and subsequent coupling of a 3rd CO mol.
Synthetic Route of 244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary