Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.
Kumari, Annu;Dehaen, Wim;Chopra, Deepak;Dey, Swapan research published 《 Imidazopyridine-fluoride interaction: solvent-switched AIE effects via S···O conformational locking》, the research content is summarized as follows. Convenient and straightforward methods have been developed for the detection and quant. estimation of fluoride anions by two novel imidazopyridine-based carboxamides (C1 and C2) in organic and aqueous media. The synthesized mols. exhibit high selectivity and enhanced sensitivity towards recognizing fluoride ions through the ‘turn on’ fluorogenic mode. The fluoride ion-driven deprotonation of the N-H proton and the subsequent spectral changes have been characterized by 1H and 19F NMR spectroscopic techniques. Single-crystal XRD elucidates the structural evidence for deprotonation upon the addition of fluoride anions, wherein C1.S (C1-.2H2O.TBA+) and C2.S (C2-.2H2O.TBA+) salts were generated. Accordingly, C1 unveiled broad absorption bands at λmax 340 nm, whereas C2 displayed similar bands at λmax 308 nm in UV-vis spectra. The peaks shift to λmax 350 nm and λmax 341 nm after deprotonation. C1 itself exhibits the aggregation induced emission (AIE) phenomenon in water-DMSO (1 : 1). This is the first report of an imidazopyridine moiety being involved in a solvent-switched AIE effect via S···O conformational locking. UV-vis and fluorescence spectra of the compounds were obtained to predict the stoichiometry, binding constant, and the limit of detection (LOD). The actual structures of carboxamides and the resulting deprotonated carboxamide salts have been confirmed by single-crystal X-ray diffraction data. Different intra- and intermol. H-bonds, namely O-H···N, O-H···O, N-H···O, C-H···N and C-H···O, play a significant role in the crystal packing of these compounds
Recommanded Product: Ethyl 3-bromo-2-oxopropanoate, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary